|
|
|
|
Fowke Lab Home | Lab Members |
Lab Gallery
|
|
|
|
Technicians | Fellows |
Students | Former Lab Members | Honours
|
Steve Wayne
Email: waynesa@ms.umanitoba.ca
Supervisor: |
Dr. Keith Fowke
|
|
Position: |
Technician |
|
Degrees obtained: |
- B.Sc. Microbiology - University of Manitoba
|
Current Project: |
Tech Support
|
About: Steve is
a research technician for Dr. Keith Fowke. He has a 4 year BSc. major in
microbiology from the University of Manitoba. Steve provides tech support and have been
involved in many projects that include many techniques. This includes
molecular biology, cytometry, cell culture, and other protocols. I also run
and overlook our BD FACScailbur cytometer and Epics Elite sorter in level 3. He
has recently begun using Luminex bead technology to study samples.
|
Andrew Stalker
Email: atstalker@gmail.com
Supervisor: |
Dr. Keith Fowke |
|
Position: |
Technician |
 |
Degrees obtained: |
- B.Sc. (Hons.) Genetics -
University of Manitoba
|
Current Project: |
SNP detection and analysis through gene sequencing |
About: Andrew is a new technician to the Fowke lab. His major focus is assisting with molecular biology and genetics based projects. |
|
Yoav Keynan
Email: Keynany@yahoo.com
Supervisor: |
Dr. Keith Fowke
|
|
Position: |
Clinical Fellow and
PhD Candidate |
|
Degrees obtained: |
- Doctor of Medicine- Faculty of Health Sciences, Ben-Gurion University of the Negev
- 1999-2004 –Residency- Division of Medicine - Carmel Medical Center- Haifa, Israel.
|
Current Project: |
Using suspension bead array for antibody detection and flow-cytometry for CMI
|
About:
Using suspension bead array for antibody detection and flow-cytometry for CMI the antigen specific responses to HIV and Influenza are determined. The influenza and HIV specific responses of HIV resistant commercial sex workers will be determined before and after mucosal influenza vaccine challenge
|
Julie Lajoie
Email:
Supervisor: |
Dr. Keith Fowke
|
|
Position: |
Postdoctoral Fellow |
 |
Degrees obtained: |
- M.Sc. Microbiology -
Université de Montréal
- Research Assistant -
Laboratoire d'immunogénétique
- PhD. Virology -
Université de Montréal
|
Current Project: |
Study of the mucosal immunology in highly exposed seronegative commercial sex workers
|
About:
The majority of new HIV infection occurs via heterosexual transmission. Understanding the factors influencing the susceptibility/protection to HIV infection is important in order to develop a safe and efficient compound to prevent HIV infection. Despite to be at high risk of HIV acquisition, some individuals remain HIV uninfected. This study aims to understanding the immune factor at the female genital tract compartment that might explain this protection against HIV infection.
|
Genevieve Boily-Larouche
Email: genevieve.boily.larouche@gmail.com
Supervisor: |
Dr. Keith Fowke
|
|
Position: |
Postdoctoral Fellow |
 |
Degrees obtained: |
- PhD. Virology and Immunology -
University of Montreal
|
Current Project: |
Drivers and Consequences of Immune Quiescence
in HIV Exposed Seronegative Individuals from Nairobi, Kenya.
|
About:
|
|
Jennifer Juno
Email: umjuno@cc.umanitoba.ca
Supervisor: |
Dr. Keith Fowke
|
|
Position: |
PhD Candidate |
 |
Degrees obtained: |
- B.Sc.(Hons.) Molecular Biology -
University of Toronto
|
Current Project: |
Impact of Genetic Variation at the CD4 Locus on HIV Susceptibility and Disease Progression
|
About:
Our lab has previously identified a polymorphism in the CD4 gene that is associated with increased susceptibility to HIV infection and accelerated disease progression. A nearby gene, GNB3, mediates signaling cascades initiated by the HIV co-receptors CCR5 and CXCR4 and contains multiple polymorphisms that regulate its function. The CD4 gene is also in close proximity to LAG-3 (Lymphocyte activation gene 3), a T cell activation and exhaustion marker whose role in HIV infection is not well described. This project will investigate whether the GNB3 825T polymorphism is associated with HIV susceptibility or disease progression among high- and low-risk Kenyan women, and will characterize the expression and function of LAG-3 on immune subsets during HIV infection and ARV therapy.
|
Courtney Bell
Email: umbell4@cc.umanitoba.ca
Supervisor: |
Dr. Keith Fowke |
|
Position: |
M.Sc. Graduate Student |
 |
Degrees obtained: |
- B.Sc. (Hons.) Biology -
University of Winnipeg
- B.Sc. Biochemistry -
University of Winnipeg
|
Current Project: |
|
About: |
Abdi Abdullahi
Email: aabdul03@gmail.com
Supervisor: |
Dr. Keith Fowke |
|
Position: |
M.Sc. Graduate Student |
 |
Degrees obtained: |
- B.Sc.Microbiology -
University of Manitoba
|
Current Project: |
Investigation of Immune Quiescence: Assessing the role of T regulatory cells a in HIV Exposed Sero-negative (HESN) subjects |
About: Tregs are a subset of CD4+ cells that have important roles in central tolerance and maintenance of homeostasis of immune cells. They have been shown to suppress CD4+ and CD8+ T cells responses to HIV and other antigens. Recently it has been shown that HIV resistant women have higher levels of CD4+CD25+FOXP3+ Tregs compared to HIV-susceptible women. The focus on my project will be to assess the role of Tregs in the Immune Quiescence model of resistance, which suggests that a reduced activation state is protective against HIV infection. To assess if elevated Tregs are contributing to the Immune Quiescent phenotype in HIV resistant women, Tregs will be depleted from PBMCs and analyzed for activation, proliferation and cytokine expression by flow cytometry following stimulation with different activating agents .We hypothesize Treg depletion will result in higher activation, proliferation and cytokine responses, suggesting that Tregs have a suppressive role in HIV resistant women and thus might be contributing to Immune Quiescence. |
|
|
Catherine Card
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Student |
| Term: |
2005 - 2012 |
| Degrees obtained: |
- PhD - University of Manitoba
|
| Project: |
The role of regulatory T cells in HIV infection and resistance |
| Outcome: |
PDF at University of Lausanne, Switzerland |
Paul McLaren
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Student |
| Term: |
2000 - 2008 |
| Degrees obtained: |
- M.Sc. - University of Manitoba
- PhD - University of Manitoba
|
| Project: |
The role of regulatory T cells in HIV infection and resistance |
| Outcome: |
PDF at Harvard Medical School |
Conar O'Neil
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Summer Student |
| Term: |
2006 - 2008 |
| Project: |
CD4 Polymorphism Detection Optimization
Influenza Antibody Responses |
| Outcome: |
Entered Med School |
Sandra Koesters
Email: umkoest0@cc.umanitoba.ca
| Supervisor: |
Dr. Keith Fowke
|
|
| Position: |
Student |
| Term: |
2000 - 2007 |
| Degrees obtained: |
- M.Sc. - University of Manitoba
- PhD - University of Manitoba
|
| Project: |
Mechanisms of HIV disease progression |
| Outcome: |
Research Scientist - National Microbiology Labs |
Michael Eze
Email: m.eze@uwinnipeg.ca
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Visiting Scholar |
| Term: |
2006 - 2007 |
| Project: |
Anti-viral Immunity |
| Home Institution: |
University of Winnipeg |
Interests:
- The role of reactive oxygen species and nitric oxide in vital processes, especially in cellular immunity and pathogenesis in infectious disease states (e.g., malaria and brucellosis).
- The effects of oxidative stress modulating chemical agents on fatty acid synthesis as well as on cerulenin (antibiotic) susceptibility in Escherichia coli and Azotobacter vinelandii.
- Currently interested in, and engaged in HIV/AIDS research with Dr. Keith Fowke’s laboratory.
|
Stu Skinner
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Clinical Fellow |
| Term: |
2006 - 2007 |
| Project: |
Assessment of humoral immune responses
to HIV elite controllers |
| Outcome: |
Assistant Professor, Dept. of Medicine -
University of Saskachewan |
Francoise Vouriot
| Supervisor: |
Dr. Keith Fowke |
| Position: |
M.Sc. Student |
| Term: |
2002-2005 |
| Honours: |
- 2002/4 NSERC National Studentship - $17,300
- 2003 Faculty of Graduate Studies Travel Award
- 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
- 2005 Manitoba Medical Service Foundation Award for Excellence in Research by a Masters student. $1000.
|
| Project: |
Exploring the role of CD4 868T in mother to child
transmission of HIV |
| Outcome: |
High School Science Teacher |
Judie Alimonti
| Supervisor: |
Dr. Keith Fowke |
| Position: |
Postdoctoral Fellow |
| Term: |
2001-2005 |
| Honours: |
- 2001 MHRC Fellowship
- 2001/03 CIHR Postdoctoral Fellowship $35,000/yr
- 2002 admitted to the ICID/CIHR National Training Program
in Infectious Diseases
|
| Project: |
Defining HIV-specific
CD4+ T-helper epitopes in HIV-resistant and HIV-infected individuals. |
| Outcome: |
Research Biologist - National Microbiology Lab |
Jennifer Athayde
| Supervisor: |
Dr. Keith Fowke
|
| Position: |
B.Sc. Medicine Student |
| Term: |
2002-2004 |
| Honours: |
- 2004 Morris Newman Memorial Award for First Term B.Sc.(Med) Presentation $1000
|
| Project: |
Determine
the role of immunoglobulin G subtypes in HIV disease progression. |
| Outcome: |
Graduated |
Other Former Lab Members
- Jon Bellas - 2000-2001
- Jared Bullard - 2001-2002
- Tamar Davis - 2005
- Makobu Kimani - 2002
- Sarah Myk - 2001-2003
- Mariel Plummer - 2002-2003
|
Ms. Catherine Card
- 2005/6 Manitoba Health Research Council Studentship $17,850
- 2006-07 CIHR Graduate Student Award-Master's
- 2006 Poster Presentation Award-International Centre for Infectious Disease
Retreat
- 2007 Public Health Agency of Canada Research Forum Best Student Poster
Award
- 2007 First Place Award for Dept of Medical Microbiology Journal Club
Presentaiton
- 2007-10 CIHR Graduate Student Award-PhD
Ms. Sandra Koesters
- 2000/2001 The Ade and Co. Award for Outstanding Journal Club Presentation
- 2001/02 Allan Ronald Graduate Fellowship - $7,000
- 2001 Faculty of Graduate Studies Travel Award
- 2002/04 Manitoba Health Research Council Graduate Fellowship - $16,000
- 2002- admitted to the ICID/CIHR National Training Program in Infectious Diseases
- 2003-2006 CIHR Doctoral Research Award
- 2003 Canada Student Health Research Forum – Manitoba Poster Competition Prize
- 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
- 2007 Manitoba Medical Services Foundation Major Award for PhD Thesis
in Medicine
Mr. Paul McLaren
- 2000 Health Sciences Centre Foundation Studentship $15,000
- 2001/2 University of Manitoba Graduate Fellowship – declined
- 2001/03 Manitoba Health Research Council Graduate Fellowship - $16,000
- 2002- admitted to the ICID/CIHR National Training Program in Infectious Diseases
- 2002/2003 The Ade and Co. Award for Outstanding Journal Club Presentation
- 2003-2006 CIHR Doctoral Research Award
- 2004 Canada Student Health Research Forum – Manitoba Poster Competition Prize
- 2006 Oral Presentation Award-International Centre for Infectious Disease
Retreat
Mr. Julias Oyugi
- 2004/5 Manitoba Health Research Council Studentship $17,850
- 2004 Admitted to CIHR/International Centre for Infectious Disease National Training Program
- 2006 Public Health Agency of Canada National Conference - Poster Prize Winner $250
- 2006 New Investigator Award – Basic Science Category. Canadian Association for HIV Research Annual Meeting 2006, $1000
- 2006-07 Health Sciences Centre foundation Graduate Scholarship
- 2006 Poster Presentation Award-International Centre for Infectious Disease
Retreat
Ms. Jennifer Juno
- 2007-08 National Science and Engineering Research Council (NSERC) Canada Graduate Sholarship (CGS M)
Mr. Jonothan Bellas
- 2000 Morris Newman Memorial Award for First Term B.Sc. (Med) Presentation
- 2001 Award for Excellence in B.Sc. (Med) final presentation
Ms. Jared Bullard
- 2001 Morris Newman Memorial Award for First Term B.Sc. (Med) Presentaion
- 2002 Merck Sharp & Dohme Scholarship for Best Basic Science Project
- 2002 National Student Research Forum Tracel Award to Galveston 2003
- 2002 Nicholson Prize for Best Overall Project
Ms. Jennifer Athayde
- 2004 Morris Newman Memorial Award for First Term B.Sc.(Med) Presentation
Mr. Tavis Bodnarchuk
- 2007 Mr. Justice James E. Wilson Award for outstanding performance in
the first year of BSc (Med) program.
Ms. Francoise Vouroit
- 2002/4 NSERC National Studentship
- 2003 Faculty of Graduate Travel Award
- 2004 Canada Student Health Research Forum-Manitoba Poster Competition
Prize
- 2005 Manitoba Medical Service Foundation Award for Excellence in Research
by a Master student
Mr. Tavis Bodnarchuk
- 2007 Mr. Justice James E. Wilson Award for outstanding performance in
the first year of BSc (Med) program.
Back to Top
|
|
